Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL28856614 | 0.96 | LMNA (0.50) | L3MBTL1LMNAHTTCTDSP1CYP1A2 | |
| SCHEMBL8273082 | 0.80 | L3MBTL1 (0.56) | L3MBTL1LMNAHTTCTDSP1CYP1A2 | |
| SCHEMBL29935484 | 0.79 | F2 (0.42) | HTTCTDSP1BACE1 | |
| SCHEMBL423891 | 0.77 | L3MBTL1 (0.71) | L3MBTL1LMNAHTTCTDSP1CYP1A2 | |
| SCHEMBL29475389 | 0.76 | L3MBTL1 (0.73) | L3MBTL1LMNAHTTCTDSP1CYP1A2 | |
| SCHEMBL56875 | 0.76 | L3MBTL1 (0.73) | L3MBTL1LMNAHTTCTDSP1CYP1A2 | |
| SCHEMBL2744804 | 0.75 | MEN1 (0.49) | CYP1A2BACE1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12572410 | 0.73 | HTT (0.50) | L3MBTL1LMNAHTTCTDSP1CYP1A2 | |
| SCHEMBL18949729 | 0.73 | HTT (0.56) | L3MBTL1LMNAHTTCTDSP1CYP1A2 | |
| SCHEMBL30524940 | 0.73 | LMNA (0.68) | L3MBTL1LMNAHTTCTDSP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793025-B | Method for modifying amino in molecule by oxazoline quaternary ammonium salt and application thereof | 中国科学院上海药物研究所 | 2022-09-23 | — | — | CN | disclosed |