Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711520 | 0.75 | MEN1 (0.52) | MEN1KMT2ALPAR1LPAR2EPHX2 | |
| SCHEMBL18701988 | 0.72 | EPHX2 (0.48) | PKMMEN1KMT2AEPHX2MAPT | |
| SCHEMBL1939095 | 0.72 | L3MBTL1 (0.51) | MEN1KMT2ALMNAMAPK1MAPT | |
| SCHEMBL8103882 | 0.68 | FYN (0.42) | MEN1KMT2AEPHX2LMNAMAPK1 | |
| SCHEMBL10724375 | 0.68 | POLB (0.67) | PKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30011251 | 0.68 | LPAR1 (0.52) | PKMMEN1KMT2ALPAR1LPAR2 | |
| SCHEMBL12169349 | 0.67 | L3MBTL1 (0.69) | PKMMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1940087 | 0.67 | HTT (0.46) | MEN1KMT2AEPHX2LMNAMAPK1 | |
| SCHEMBL14132815 | 0.67 | KDM2B (0.62) | PKMMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10263618 | 0.66 | MEN1 (0.47) | PKMMEN1KMT2ASIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073073-A1 | THIENOPYRIMIDINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2022-10-19 | — | — | EP | claimed |