Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 7/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108257 | 0.79 | DRD3 (0.48) | FYNALDH1A1CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7450611 | 0.78 | FYN (0.45) | FYNALDH1A1CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7457739 | 0.76 | ALDH1A1 (0.46) | FYNALDH1A1CYP2D6CYP2C9ALOX15 | |
| SCHEMBL6431031 | 0.70 | MEN1 (0.54) | DRD3DRD2DRD4MEN1KMT2A | |
| SCHEMBL7449830 | 0.69 | MCOLN3 (0.44) | FYNDRD3HTR1A | |
| SCHEMBL7455176 | 0.67 | ALDH1A1 (0.50) | ALDH1A1MAPK1MEN1KMT2ALMNA | |
| SCHEMBL7452274 | 0.64 | FYN (0.58) | FYNALDH1A1CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7403093 | 0.63 | DRD3 (0.59) | FYNALDH1A1CYP2D6CYP2C9ALOX15 | |
| SCHEMBL8693035 | 0.63 | FYN (0.70) | FYNALDH1A1CYP2D6CYP2C9ALOX15 | |
| SCHEMBL7404669 | 0.62 | FYN (0.51) | FYNALDH1A1CYP2D6CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6084130-A | FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-04 | — | — | US | disclosed |