Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299141 | 0.88 | RAB9A (0.52) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL289699 | 0.87 | KDM4E (0.61) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3826145 | 0.82 | LMNA (0.55) | RAB9AALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL290278 | 0.81 | KDM4E (0.66) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL290403 | 0.80 | APP (0.55) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL288793 | 0.79 | KDM4E (0.56) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL289321 | 0.79 | CYP3A4 (0.62) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL289747 | 0.78 | CYP3A4 (0.61) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3827647 | 0.77 | KDM4E (0.69) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL288141 | 0.76 | KDM4E (0.78) | RAB9AALDH1A1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |