Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289635 | 0.89 | KDM4E (0.57) | APPRAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL4741823 | 0.87 | RAB9A (0.70) | RAB9AMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL290306 | 0.85 | ALDH1A1 (0.59) | APPRAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL299363 | 0.80 | RAB9A (0.55) | RAB9AALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL289321 | 0.77 | CYP3A4 (0.62) | RAB9AMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL299141 | 0.77 | RAB9A (0.52) | RAB9AMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL289964 | 0.77 | SMN1; SMN2 (0.57) | RAB9AMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15656938 | 0.77 | RAB9A (0.63) | RAB9AMAPTALDH1A1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL289747 | 0.76 | CYP3A4 (0.61) | RAB9AMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL290134 | 0.76 | KDM4E (0.75) | RAB9AMAPTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |