Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 19/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008778 | 1.00 | LTA4H (0.74) | LTA4HKCNH2HRH3 | |
| SCHEMBL13657536 | 0.88 | LTA4H (0.77) | LTA4HKCNH2 | |
| SCHEMBL1008985 | 0.85 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL1008850 | 0.76 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL1892429 | 0.76 | LTA4H (0.68) | LTA4HKCNH2 | |
| SCHEMBL1008192 | 0.76 | LTA4H (0.68) | LTA4HKCNH2 | |
| SCHEMBL1008332 | 0.76 | LTA4H (0.62) | LTA4HKCNH2 | |
| SCHEMBL14640183 | 0.75 | LTA4H (0.80) | LTA4HKCNH2 | |
| SCHEMBL1009222 | 0.75 | LTA4H (0.78) | LTA4HKCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL2250147 | 0.75 | LTA4H (0.67) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220226304-A1 | Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase | ALKAHEST, INC. | 2022-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220226304-A1 | Treatment of Aging-Associated Disease with Modulators of Leukotriene A4 Hydrolase | LTA4H, LTB4R, LTC4S | LTA4H 1/4885KCNH2 3977/4885HRH3 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.