Phenol

Phenol

SCHEMBL2993673

Cc1cc(C(C)(C)c2cc(C)c(O)c(C)c2)cc(C)c1O.Oc1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.57
ESR2 Q92731 7/20 0.57
CYP3A4 P08684 3/20 0.57
ALDH1A1 P00352 3/20 0.57
HPGD P15428 2/20 0.48
TSHR P16473 2/20 0.48
HSD17B10 Q99714 2/20 0.48
AR P10275 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR6 P50406 1/20 0.48
ESRRG P62508 1/20 0.48
SLC6A3 Q01959 1/20 0.48
TTR P02766 1/20 0.47
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023357 0.89 ESR1 (0.59) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL5086131 0.87 ESR1 (0.69) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL728306 0.85 ESR1 (0.70) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL69586 0.84 ALDH1A1 (0.56) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL7748954 0.84 ESR1 (0.55) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL686758 0.82 ESR1 (0.60) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL29472991 0.82 ALDH1A1 (0.54) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL2618674 0.82 ALDH1A1 (0.54) ESR1ESR2CYP3A4ALDH1A1HPGD
SCHEMBL237756 0.81 ESR1 (0.61) ESR1ESR2CYP3A4ALDH1A1HPGD
Phenol SCHEMBL27191078 0.81 ESR1 (0.79) ESR1ESR2CYP3A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3046942-B1 POLYURETHANE FOAM AND ASSOCIATED METHOD AND ARTICLE SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-10-23 EP claimed
EP-3027667-B1 RIGID FOAM AND ASSOCIATED ARTICLE SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-03-21 EP claimed
EP-1969030-B1 POLY (ARYLENE ETHER) COPOLYMER SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-01-25 EP claimed
US-7786219-B2 Cyanate-terminated polyphenylene ether MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-08-31 US disclosed
US-20100048826-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI 2010-02-25 US disclosed
US-7632912-B2 Carboxylic acid-modified bisphenol epoxy di(meth)acrylate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-12-15 US disclosed
US-20090205856-A1 Carboxylic Acid-Modified Bisphenol Epoxy Di(meth)acrylate ISHII KENJI 2009-08-20 US disclosed
US-7560518-B2 (Meth)acrylated epoxy-terminated polyphenylene ether MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-07-14 US disclosed
US-20080269427-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI 2008-10-30 US disclosed
US-7393904-B2 (Meth)acrylate-terminated polyphenylene ether MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-07-01 US disclosed
US-20080033117-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI 2008-02-07 US disclosed
US-7276563-B2 Polyphenylene ether oligomer compound, derivatives thereof and use thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-10-02 US disclosed
US-20050065241-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof ISHII KENJI (JP) 2005-03-24 US disclosed
US-6835785-B2 Curable end groups, such as allyl, (meth)acryloyloxy, glycidyloxy and cyanate groups; printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-12-28 US disclosed
US-20030194562-A1 Polyphenylene ether oligomer compound, derivatives thereof and use thereof MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090205856-A1 Carboxylic Acid-Modified Bisphenol Epoxy Di(meth)acrylate EED, MMAB, CAD ESR1 177/4885ESR2 630/4885CYP3A4 2373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.