Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.65 |
| ▸ | CNR2 | P34972 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15622712 | 0.86 | KDM4E (0.68) | MTNR1AMTNR1BCNR2KMT2AKDM4E | |
| SCHEMBL8301465 | 0.86 | MTNR1A (0.72) | MTNR1AMTNR1BCNR2KMT2AKDM4E | |
| SCHEMBL7879659 | 0.85 | MTNR1A (0.61) | MTNR1AMTNR1BCNR2KMT2AMCL1 | |
| SCHEMBL7882170 | 0.84 | MTNR1A (0.67) | MTNR1AMTNR1BCNR2KMT2AKDM4E | |
| SCHEMBL30403537 | 0.84 | MTNR1A (0.62) | MTNR1AMTNR1BCNR2KMT2AKDM4E | |
| SCHEMBL29937398 | 0.83 | MTNR1A (0.65) | MTNR1AMTNR1BCNR2KMT2AKDM4E | |
| SCHEMBL1422759 | 0.83 | MTNR1A (0.65) | MTNR1AMTNR1BKMT2AKDM4ECRHBP | |
| SCHEMBL6752492 | 0.82 | ALDH1A1 (0.63) | CNR2MCL1 | |
| SCHEMBL4930790 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BCNR2KMT2AKDM4E | |
| SCHEMBL11211402 | 0.82 | ALDH1A1 (0.71) | MTNR1AMTNR1BCNR2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533929-B | Indole macrocyclic derivatives, preparation method and medical application thereof | 福建盛迪医药有限公司 | 2022-09-16 | — | — | CN | disclosed |