Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.93 |
| ▸ | GAA | P10253 | 5/20 | 0.93 |
| ▸ | HTT | P42858 | 4/20 | 0.93 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | S100B | P04271 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136241 | 1.00 | ALDH1A1 (0.93) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| SCHEMBL3485151 | 0.98 | ALDH1A1 (0.96) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| SCHEMBL1110600 | 0.98 | ALDH1A1 (0.96) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL29979151 | 0.96 | ALDH1A1 (1.00) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL23043584 | 0.96 | ALDH1A1 (1.00) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| SCHEMBL1136197 | 0.83 | ALDH1A1 (0.67) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| SCHEMBL30198288 | 0.83 | ALDH1A1 (1.00) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| SCHEMBL7429136 | 0.83 | ALDH1A1 (0.67) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| SCHEMBL30431849 | 0.83 | ALDH1A1 (0.67) | ALDH1A1GAAHTTL3MBTL1KDM4E | |
| SCHEMBL8714328 | 0.83 | ALDH1A1 (1.00) | ALDH1A1GAAHTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | University of Florida Research Fooundation, Incorporated (US) | 2024-07-25 | — | — | US | disclosed |
| WO-2022226133-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246943-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | IL6, IL6ST, IL36G | ALDH1A1 2068/4885GAA 545/4885HTT 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.