SCHEMBL2993799

SCHEMBL2993799

Cn1nc(C(F)(F)F)c(C(=O)Nc2ccccc2-c2cc(F)c(F)c(F)c2)c1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
NPSR1 Q6W5P4 7/20 0.46
CYP1A2 P05177 5/20 0.46
CYP3A4 P08684 5/20 0.46
CYP2C19 P33261 5/20 0.46
CYP2C9 P11712 4/20 0.46
GAA P10253 4/20 0.46
CYP2D6 P10635 3/20 0.46
HPGD P15428 1/20 0.46
CHRM3 P20309 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
NTRK1 P04629 1/20 0.42
ALDH1A1 P00352 3/20 0.41
POLB P06746 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.40
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
MAPT P10636 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3005746 0.90 LMNA (0.64) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL1085473 0.89 LMNA (0.48) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL4918707 0.88 LMNA (0.52) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL2997208 0.86 LMNA (0.51) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL4098297 0.86 MEN1 (0.52) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL29445414 0.86 LMNA (0.51) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL4920399 0.86 LMNA (0.52) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL1134839 0.86 CHRM3 (0.46) LMNACYP1A2CYP3A4CYP2C19CYP2C9
SCHEMBL4916941 0.85 LMNA (0.50) LMNANPSR1CYP1A2CYP3A4CYP2C19
SCHEMBL27707930 0.84 LMNA (0.47) LMNANPSR1CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-9439435-B2 Method for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides FMC CORPORATION (US) 2016-09-13 US claimed
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20160183538-A1 MICROBIAL COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2016-06-30 US claimed
US-20150313235-A1 Method for Controlling Weeds Using Formulations Containing Fluthiacet-Methyl and HPPD Herbicides FMC CORP (US) 2015-11-05 US claimed
EP-2285779-B1 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-03-27 EP claimed
US-8350046-B2 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-01-08 US claimed
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil BASF SE (DE) 2010-08-05 US claimed
EP-2205082-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2010-07-14 EP claimed
US-20100048403-A1 Method of inducing virus tolerance of plants BASF SE (DE) 2010-02-25 US claimed
EP-2109362-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2009-10-21 EP claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO claimed
EP-4046491-B1 CONSUMER CARE PRODUCT FMC CORP (US) 2026-04-29 EP disclosed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160186273-A1 BACILLUS AMYLOLIQUEFACIENS RTI301 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE BTF3, MYB, AGXT LMNA 3555/4885NPSR1 3683/4885CYP1A2 951/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC LMNA 3370/4885NPSR1 4014/4885CYP1A2 327/4885
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil CBR3, CBX3, BRD3 LMNA 2608/4885NPSR1 2390/4885CYP1A2 730/4885
US-20100048403-A1 Method of inducing virus tolerance of plants CBR3, CBR1, CYC1 LMNA 4263/4885NPSR1 1136/4885CYP1A2 265/4885
US-20160183537-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC LMNA 3370/4885NPSR1 4014/4885CYP1A2 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.