SCHEMBL1134839

SCHEMBL1134839

Cc1nn(C)c(F)c1C(=O)Nc1ccccc1-c1cc(F)c(F)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 4/20 0.46
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
HTT P42858 3/20 0.43
TSHR P16473 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPT P10636 2/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 3/20 0.42
NPC1 O15118 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4C Q9H3R0 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM1 P11229 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4453379 0.90 ALDH1A1 (0.46) CHRM3ALDH1A1MEN1KMT2AHTT
SCHEMBL1134832 0.89 ALDH1A1 (0.47) CHRM3ALDH1A1MEN1KMT2AHTT
SCHEMBL11930691 0.88 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL4449334 0.87 ALDH1A1 (0.43) CHRM3ALDH1A1MEN1KMT2AHTT
SCHEMBL13455819 0.86 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AHTTTSHR
SCHEMBL2993799 0.86 LMNA (0.50) CHRM3ALDH1A1MEN1KMT2AHTT
SCHEMBL2998458 0.86 CHRM3 (0.44) CHRM3ALDH1A1MEN1KMT2AHTT
SCHEMBL4456702 0.86 TACR1 (0.47) CHRM3ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL29445384 0.85 CHRM3 (0.46) CHRM3ALDH1A1MEN1KMT2AHTT
SCHEMBL1134827 0.85 CHRM3 (0.46) CHRM3ALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-9439435-B2 Method for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides FMC CORPORATION (US) 2016-09-13 US claimed
EP-2285779-B1 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-03-27 EP claimed
US-8350046-B2 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-01-08 US claimed
EP-2285779-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2011-02-23 EP claimed
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil BASF SE (DE) 2010-08-05 US claimed
EP-2205082-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2010-07-14 EP claimed
US-20100048403-A1 Method of inducing virus tolerance of plants BASF SE (DE) 2010-02-25 US claimed
WO-2009135860-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2009-11-12 WO claimed
EP-2109362-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2009-10-21 EP claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
WO-2008098928-A2 METHOD OF INDUCING VIRUS TOLERANCE OF PLANTS BASF SE (DE) 2008-08-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC CHRM3 487/4885ALDH1A1 4545/4885MEN1 3107/4885
US-20100197741-A1 Ternary Fungicidal Compositions Comprising Boscalid and Chlorothalonil CBR3, CBX3, BRD3 CHRM3 664/4885ALDH1A1 2714/4885MEN1 2142/4885
US-20100048403-A1 Method of inducing virus tolerance of plants CBR3, CBR1, CYC1 CHRM3 1239/4885ALDH1A1 2425/4885MEN1 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.