Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619272 | 0.83 | LOXL2 (0.52) | ADORA2BPDCD1CD274NR3C2 | |
| SCHEMBL3506919 | 0.80 | CD274 (0.41) | ADORA2BPDCD1CD274KDM1AHDAC1 | |
| SCHEMBL1413439 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2ADORA2A | |
| SCHEMBL30044994 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2ADORA2A | |
| SCHEMBL2560682 | 0.78 | ADORA2A (0.43) | CYP11B1CYP11B2ADORA2A | |
| SCHEMBL25489462 | 0.77 | PDCD1 (0.38) | ADORA2BKDM4EALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28478178 | 0.77 | CYP11B1 (0.46) | ADORA2BCYP11B1CYP11B2ADORA2A | |
| SCHEMBL27209742 | 0.76 | HRH3 (0.37) | KDM4EALDH1A1HPGDCYP11B1CYP11B2 | |
| SCHEMBL1413419 | 0.75 | GRIN2B (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL19911768 | 0.75 | CYP11B2 (0.47) | KDM4EPDCD1CD274CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500795-A | Receptor interacting protein 1 inhibitor, preparation and application thereof | 维泰瑞隆有限公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-4308555-A1 | RECEPTOR-INTERACTING PROTEIN 1 INHIBITORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022194259-A1 | RECEPTOR-INTERACTING PROTEIN 1 INHIBITORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2022-09-22 | — | — | WO | disclosed |