Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.46 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998894 | 0.90 | GRM3 (0.59) | HDAC4L3MBTL3L3MBTL1GRM3PARP10 | |
| SCHEMBL3001297 | 0.90 | GRM5 (0.60) | GRM5L3MBTL3L3MBTL1GRM3PARP10 | |
| SCHEMBL2993890 | 0.87 | MGLL (0.55) | HDAC4GRM5L3MBTL3L3MBTL1PDK2 | |
| SCHEMBL19144451 | 0.87 | MGLL (0.55) | HDAC4GRM5L3MBTL3L3MBTL1PDK2 | |
| SCHEMBL10195732 | 0.83 | KMT2A (0.62) | HDAC4GRM5L3MBTL3GRM3 | |
| SCHEMBL1447833 | 0.83 | MGLL (0.55) | HDAC4GRM5L3MBTL3L3MBTL1PDK2 | |
| SCHEMBL2825708 | 0.83 | NPC1 (0.62) | HDAC4L3MBTL1GAA | |
| SCHEMBL13486885 | 0.83 | KMT2A (0.62) | HDAC4GRM5L3MBTL3GRM3 | |
| SCHEMBL21590166 | 0.83 | L3MBTL3 (0.59) | HDAC4GRM5L3MBTL3L3MBTL1PDK2 | |
| SCHEMBL968219 | 0.83 | L3MBTL3 (0.59) | HDAC4GRM5L3MBTL3L3MBTL1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-07-29 | — | — | US | claimed |
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-12-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276496-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | HDAC4 783/4885GRM5 4379/4885L3MBTL3 4109/4885 |
| US-20100190773-A1 | Anti-Cytokine Heterocyclic Compounds | MAPKAPK2, MAP4K2, MAP3K2 | HDAC4 783/4885GRM5 4379/4885L3MBTL3 4109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.