Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 4/20 | 0.45 |
| ▸ | CYCS | P99999 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29472187 | 0.98 | TERT (0.46) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL2901359 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29437842 | 0.96 | TERT (0.45) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL30558880 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL6865971 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL21493256 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29582816 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29353372 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29648942 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL174717 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111040082-B | Viscosity index improver and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-111040843-B | Gasoline engine oil composition and preparation method thereof | 中国石油化工股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-111040082-B | Viscosity index improver and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-10-21 | — | — | CN | disclosed |