Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.45 |
| ▸ | TERT | O14746 | 4/20 | 0.45 |
| ▸ | CYCS | P99999 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6865971 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL29939540 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL21493256 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL30558880 | 0.96 | TOP1 (0.45) | TOP1TERTCYCSENPP2 | |
| SCHEMBL174717 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29353372 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29582816 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29648942 | 0.96 | TERT (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL1313450 | 0.94 | TERT (0.46) | TOP1TERTCYCSENPP2 | |
| SCHEMBL4020034 | 0.94 | TERT (0.46) | TOP1TERTCYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122706-A1 | ARRAY USING COLOR REACTION OF CHEMICAL COMPOUNDS | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2012-05-17 | — | — | US | claimed |
| US-7297657-B2 | Process for the preparation of N-(phosphonomethyl)glycine by oxidizing N-substituted N-(phosphonomethyl)glycine | MONSANTO TECHNOLOGY LLC (US) | 2007-11-20 | — | — | US | claimed |
| EP-1716923-A1 | Oxidation catalyst for making glyphosate | Monsanto Technology, LLC (US) | 2006-11-02 | — | — | EP | claimed |
| EP-1062221-B1 | PROCESS FOR MAKING GLYPHOSATE BY OXIDIZING N-SUBSTITUTED GLYPHOSATES | MONSANTO TECHNOLOGY LLC (US) | 2006-05-10 | — | — | EP | claimed |
| US-20040143134-A1 | Process for the preparation of N-(phosphonomethyl)glycine by oxidizing N-substituted N-(phosphonomethyl)glycine | MONSANTO TECHNOLOGY LLC | 2004-07-22 | — | — | US | claimed |
| US-20010018536-A1 | Process for the preparation of n- (phosphonomethyl) glycine by oxidizing n-substituted n-(phosphonomethyl) glycine | MONSANTO TECHNOLOGY LLC | 2001-08-30 | — | — | US | claimed |
| US-6232494-B1 | CATALYTIC OXIDATION | MONSANTO COMPANY | 2001-05-15 | — | — | US | claimed |
| US-6005140-A | USING A NOBLE METAL OXIDATION CATALYST | MONSANTO COMPANY (US) | 1999-12-21 | — | — | US | claimed |
| CN-117783019-A | On-site detection method of CTC black tea production place based on solution phase color sensing array | 安徽农业大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-106290631-B | A kind of method of pigment array sensing technology Fast Evaluation magma Quality of Liquors | 江苏今世缘酒业股份有限公司 | 2018-11-27 | — | — | CN | disclosed |
| EP-2057275-B1 | ARRAY FOR RAPID DETECTION OF A MICROORGANISM | KIMBERLY CLARK CO (US) | 2017-02-01 | — | — | EP | disclosed |
| CN-106290631-A | A kind of method of pigment array sensing technology Fast Evaluation original plasm wine quality | 江苏今世缘酒业股份有限公司 | 2017-01-04 | — | — | CN | disclosed |
| EP-2331952-B1 | COLORIMETRIC SENSOR ARRAYS BASED ON NANOPOROUS PIGMENTS | UNIV ILLINOIS (US) | 2016-06-15 | — | — | EP | disclosed |
| EP-2056890-B1 | METHOD FOR DETECTING CANDIDA ON SKIN | KIMBERLY CLARK CO (US) | 2015-11-18 | — | — | EP | disclosed |
| US-6153753-A | CATALYTIC CARBOXYMETHYLATION OF A CARBAMOYL COMPOUND BY PREMIXING THE CARBAMOYL COMPOUND AND THE CARBOXYMETHYLATION CATALYST PRECURSOR FIRST, THEN ADDING THE WATER AND ALDEHYDE; FORMING N-(PHOSPHONOMETHYL)GLYCINE HERBICIDE OR PESTICIDE | MONSANTO COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
| US-6005140-A | USING A NOBLE METAL OXIDATION CATALYST | MONSANTO COMPANY (US) | 1999-12-21 | — | — | US | disclosed |
| US-5981422-A | PERFLUOROALKYLPHTHALOCYANINATO METAL COMPLEX OR 20-TETRAKIS-PENTAFLUOROPHENYL PORPHYRIN METAL COMPLEX USED AS CATALYST | EXXON RESEARCH AND ENGINEERING CO. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0633062-B1 | Fluorous multiphase catalyst or reagent systems, and processes using them | EXXON RESEARCH ENGINEERING CO (US) | 1999-09-08 | — | — | EP | disclosed |
| US-5463082-A | Fluorous multiphase systems | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1995-10-31 | — | — | US | disclosed |
| EP-0633062-A1 | Fluorous multiphase catalyst or reagent systems, and processes using them | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1995-01-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018536-A1 | Process for the preparation of n- (phosphonomethyl) glycine by oxidizing n-substituted n-(phosphonomethyl) glycine | GNMT, GRHPR, GLRA3 | TOP1 3870/4885TERT 3782/4885CYCS 865/4885 |
| US-20040143134-A1 | Process for the preparation of N-(phosphonomethyl)glycine by oxidizing N-substituted N-(phosphonomethyl)glycine | GNMT, GRHPR, GLRA3 | TOP1 3845/4885TERT 3877/4885CYCS 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.