Bixin

Bixin

SCHEMBL29939591

COC(=O)/C=C/C(C)=C\C=C\C(C)=C\C=CC=C(C)C=C/C=C(C)\C=C\C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
MAPT P10636 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
KDM4E B2RXH2 1/20 1.00
ALOX15 P16050 2/20 0.89
RECQL P46063 2/20 0.89
HSD17B10 Q99714 2/20 0.89
TSHR P16473 3/20 0.74
HCAR2 Q8TDS4 8/20 0.63
PTGS1 P23219 2/20 0.50
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
PTPN1 P18031 1/20 0.39
NR1I2 O75469 2/20 0.36
ABCC4 O15439 1/20 0.36
ABCB11 O95342 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bixin SCHEMBL42729 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL29959685 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL9939959 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL30873767 0.94 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL1463087 0.94 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL30404058 0.92 ALDH1A1 (0.85) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL3287610 0.91 ALDH1A1 (0.82) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL22344763 0.91 ALDH1A1 (0.82) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL25460630 0.87 ALDH1A1 (0.77) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL29378795 0.87 ALDH1A1 (0.77) ALDH1A1MAPTTDP1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4333650-A1 ORAL COMPOSITIONS AND RELATED METHODS FOR REDUCING THROAT IRRITATION Nicoventures Trading Limited (GB) 2024-03-13 EP disclosed
WO-2022234522-A1 ORAL COMPOSITIONS AND RELATED METHODS FOR REDUCING THROAT IRRITATION Nicoventures Trading Limited (GB) 2022-11-10 WO disclosed