Bixin

Bixin

SCHEMBL29959685

COC(=O)C=CC(C)=CC=CC(C)=CC=CC=C(C)C=CC=C(C)C=CC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
MAPT P10636 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
KDM4E B2RXH2 1/20 1.00
ALOX15 P16050 2/20 0.89
RECQL P46063 2/20 0.89
HSD17B10 Q99714 2/20 0.89
TSHR P16473 3/20 0.74
HCAR2 Q8TDS4 8/20 0.63
PTGS1 P23219 2/20 0.50
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
PTPN1 P18031 1/20 0.39
NR1I2 O75469 2/20 0.36
ABCC4 O15439 1/20 0.36
ABCB11 O95342 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bixin SCHEMBL42729 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL9939959 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL29939591 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL30873767 0.94 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL1463087 0.94 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL30404058 0.92 ALDH1A1 (0.85) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL3287610 0.91 ALDH1A1 (0.82) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL22344763 0.91 ALDH1A1 (0.82) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL25460630 0.87 ALDH1A1 (0.77) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL29378795 0.87 ALDH1A1 (0.77) ALDH1A1MAPTTDP1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564552-B2 Oral product with a basic amine and an ion pairing agent Nicoventures Trading Limited (GB) 2026-03-03 US disclosed
EP-4687501-A1 EMULSIONS FOR NICOTINE ENCAPSULATION Nicoventures Trading Limited (GB) 2026-02-11 EP disclosed
EP-4687504-A1 ORAL COMPOSITIONS AND METHODS OF MANUFACTURE Nicoventures Trading Limited (GB) 2026-02-11 EP disclosed
EP-4687503-A1 FUNCTIONALIZED FLEECE MATERIAL PRODUCTION Nicoventures Trading Limited (GB) 2026-02-11 EP disclosed
EP-4687502-A1 STARCHLESS MOLDING PROCESS FOR ORAL PRODUCTS Nicoventures Trading Limited (GB) 2026-02-11 EP disclosed
EP-4678009-A1 PREMIX CONTAINING GELLING AGENT FOR ORAL PRODUCT Nicoventures Trading Limited (GB) 2026-01-14 EP disclosed
EP-4665172-A1 ORAL PRODUCTS WITH HIGH-DENSITY LOAD Nicoventures Trading Limited (GB) 2025-12-24 EP disclosed
EP-4659595-A1 NICOTINE-POLYMER COMPLEX COMPRISING MULTIPLE NICOTINE FORMS Nicoventures Trading Limited (GB) 2025-12-10 EP disclosed
EP-4659596-A1 ORAL PRODUCTS WITH LOW FREE-BASE NICOTINE CONTENT Nicoventures Trading Limited (GB) 2025-12-10 EP disclosed
EP-4659594-A1 ORAL PRODUCTS CONTAINING MODIFIED NICOTINE-POLYMER COMPLEX Nicoventures Trading Limited (GB) 2025-12-10 EP disclosed
US-20220369688-A1 ORAL COMPOSITIONS AND RELATED METHODS FOR REDUCING THROAT IRRITATION NICOVENTURES TRADING LTD (GB) 2022-11-24 US disclosed
US-20220354785-A1 ORAL LOZENGE PRODUCTS NICOVENTURES TRADING LTD (GB) 2022-11-10 US disclosed
US-20220354155-A1 MULTI-COMPARTMENT ORAL POUCHED PRODUCT NICOVENTURES TRADING LTD (GB) 2022-11-10 US disclosed
US-20220354156-A1 ORAL POUCHED PRODUCT WITH HIGH DENSITY LOAD NICOVENTURES TRADING LTD (GB) 2022-11-10 US disclosed
US-20220347165-A1 EFFERVESCENT ORAL COMPOSITION NICOVENTURES TRADING LTD (GB) 2022-11-03 US disclosed
US-20220346434-A1 ORAL COMPOSITIONS AND METHODS OF MANUFACTURE NICOVENTURES TRADING LTD (GB) 2022-11-03 US disclosed
WO-2022229926-A1 MULTI-COMPARTMENT ORAL POUCHED PRODUCT Nicoventures Trading Limited (GB) 2022-11-03 WO disclosed
WO-2022229929-A1 ORAL PRODUCTS WITH HIGH-DENSITY LOAD Nicoventures Trading Limited (GB) 2022-11-03 WO disclosed
WO-2022224196-A1 ORALLY DISSOLVING FILMS Nicoventures Trading Limited (GB) 2022-10-27 WO disclosed
WO-2022224197-A1 EFFERVESCENT ORAL COMPOSITION Nicoventures Trading Limited (GB) 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220346434-A1 ORAL COMPOSITIONS AND METHODS OF MANUFACTURE OR10J3, OTC, ALG3 ALDH1A1 936/4885MAPT 495/4885TDP1 2200/4885
US-20220369688-A1 ORAL COMPOSITIONS AND RELATED METHODS FOR REDUCING THROAT IRRITATION SLC22A8, SLCO4C1, SLCO2A1 ALDH1A1 2237/4885MAPT 2437/4885TDP1 838/4885
US-12564552-B2 Oral product with a basic amine and an ion pairing agent SLC25A11, SLC16A7, SDHB ALDH1A1 524/4885MAPT 671/4885TDP1 2734/4885
US-20220354155-A1 MULTI-COMPARTMENT ORAL POUCHED PRODUCT TAS2R20, TAS2R5, TAS2R10 ALDH1A1 1366/4885MAPT 4734/4885TDP1 2284/4885
US-20220354785-A1 ORAL LOZENGE PRODUCTS OTC, OSGEP, OLA1 ALDH1A1 1037/4885MAPT 3174/4885TDP1 3077/4885
US-20220347165-A1 EFFERVESCENT ORAL COMPOSITION TAS2R40, TAS2R60, SOST ALDH1A1 2393/4885MAPT 1803/4885TDP1 2736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.