Bixin

Bixin

SCHEMBL9939959

COC(=O)/C=C/C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 1.00
▸ MAPT P10636 3/20 1.00
▸ TDP1 Q9NUW8 2/20 1.00
▸ KDM4E B2RXH2 1/20 1.00
▸ ALOX15 P16050 2/20 0.89
▸ RECQL P46063 2/20 0.89
▸ HSD17B10 Q99714 2/20 0.89
▸ TSHR P16473 3/20 0.74
▸ HCAR2 Q8TDS4 8/20 0.63
▸ PTGS1 P23219 2/20 0.50
▸ KEAP1 Q14145 1/20 0.48
▸ NFE2L2 Q16236 1/20 0.48
▸ PTPN1 P18031 1/20 0.39
▸ NR1I2 O75469 2/20 0.36
▸ ABCC4 O15439 1/20 0.36
▸ ABCB11 O95342 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ LMNA P02545 1/20 0.33
▸ PGR P06401 1/20 0.33
▸ TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bixin SCHEMBL29939591 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL42729 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL29959685 1.00 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL1463087 0.94 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL30873767 0.94 ALDH1A1 (1.00) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL30404058 0.92 ALDH1A1 (0.85) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL3287610 0.91 ALDH1A1 (0.82) ALDH1A1MAPTTDP1KDM4EALOX15
Bixin SCHEMBL22344763 0.91 ALDH1A1 (0.82) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL25460630 0.87 ALDH1A1 (0.77) ALDH1A1MAPTTDP1KDM4EALOX15
SCHEMBL29378795 0.87 ALDH1A1 (0.77) ALDH1A1MAPTTDP1KDM4EALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4716527-A1 A MULTIPLE UNIT ORAL DOSAGE FORM OF DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE FREE OF TITANIUM DIOXIDE Italfarmaco SpA (IT) 2026-04-01 — — EP claimed
EP-4709293-A1 SURGICAL STAPLER CARTRIDGE HAVING CARTRIDGE RETENTION FEATURES Cilag GmbH International (CH) 2026-03-18 — — EP claimed
WO-2024240747-A1 A MULTIPLE UNIT ORAL DOSAGE FORM OF DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE FREE OF TITANIUM DIOXIDE ITALFARMACO S.P.A. (IT) 2024-11-28 — — WO claimed
EP-4416861-A1 METHOD FOR CONFIGURING A TRANSMITTER DEVICE, AND TRANSMITTER DEVICE FOR IMPLEMENTING SAID CONFIGURATION METHOD ORANGE (FR) 2024-08-21 — — EP claimed
CN-113939306-B Medicament for treating bacterial infections involving biological membranes and uses thereof 德彪药业国际股份公司 2024-07-19 — — CN claimed
CN-114901745-B Colored particles 西姆莱斯股份公司 2024-03-08 — — CN claimed
WO-2023062042-A1 METHOD FOR CONFIGURING A TRANSMITTER DEVICE, AND TRANSMITTER DEVICE FOR IMPLEMENTING SAID CONFIGURATION METHOD ORANGE (FR) 2023-04-20 — — WO claimed
CN-115895334-A Strong-adhesion self-drying water-based ink and preparation method thereof 中山市华业油墨涂料有限公司 2023-04-04 — — CN claimed
EP-4110080-A1 COOKED FISH SUBSTITUTE Seafood Reboot (FR) 2023-01-04 — — EP claimed
EP-4110081-A1 RAW FISH SUBSTITUTE Seafood Reboot (FR) 2023-01-04 — — EP claimed
US-20220401341-A1 Colored particles AG, SYMRISE (DE) 2022-12-22 — — US claimed
EP-4055094-A1 PIGMENT PARTICLES Symrise AG (DE) 2022-09-14 — — EP claimed
CN-114901745-A Colored microparticles 西姆莱斯股份公司 2022-08-12 — — CN claimed
EP-4017485-A1 CANNABINOID ACID ESTER COMPOSITIONS AND USES THEREOF EPM Group, Inc. (US) 2022-06-29 — — EP claimed
WO-2026099516-A1 SMOKELESS ARTICLE IMPERIAL TOBACCO LIMITED (GB) 2026-05-15 — — WO disclosed
WO-2026099514-A1 SMOKELESS ARTICLE IMPERIAL TOBACCO LIMITED (GB) 2026-05-15 — — WO disclosed
WO-2026099515-A1 SMOKELESS ARTICLE IMPERIAL TOBACCO LIMITED (GB) 2026-05-15 — — WO disclosed
US-20150335757-A1 COLOURED DISINFECTANT PREPARATION BASED ON BISPYRIDINIUMALKANE SCHULKE & MAYR GMBH (DE) 2015-11-26 — — US disclosed
US-20140121333-A1 PERMANENT ATTACHMENT OF AGENTS TO SURFACES CONTAINING C-H FUNCTIONALITY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2014-05-01 — — US disclosed
US-20120149776-A1 PREPARATION FOR SUN PROTECTION BIOPHYTIS SA (FR) 2012-06-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149776-A1 PREPARATION FOR SUN PROTECTION BROX, UBXN1, BRIX1 ALDH1A1 2411/4885MAPT 1673/4885TDP1 3160/4885
US-20150335757-A1 COLOURED DISINFECTANT PREPARATION BASED ON BISPYRIDINIUMALKANE OR51E2, FHIT, SIGMAR1 ALDH1A1 4004/4885MAPT 2865/4885TDP1 1403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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