SCHEMBL31053019

SCHEMBL31053019

O=[N+]([O-])c1cc(Cl)c(Cl)c(Cl)c1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 6/20 0.74
TDP1 Q9NUW8 4/20 0.50
KDM4E B2RXH2 3/20 0.49
MEN1 O00255 3/20 0.49
MAPT P10636 3/20 0.49
KMT2A Q03164 3/20 0.49
PKM P14618 2/20 0.49
HTT P42858 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 4/20 0.48
TSHR P16473 2/20 0.48
HPGD P15428 2/20 0.48
MAPK1 P28482 2/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP3A4 P08684 1/20 0.47
TTR P02766 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9115584 0.85 GPR35 (1.00) GPR35TDP1KDM4EMEN1MAPT
SCHEMBL9112380 0.85 GPR35 (0.83) GPR35TDP1KDM4EMEN1MAPT
SCHEMBL9226136 0.83 GPR35 (0.74) GPR35TDP1KDM4EMEN1MAPT
SCHEMBL6010888 0.82 GPR35 (0.61) GPR35TDP1KDM4EMEN1MAPT
SCHEMBL3650611 0.80 TDP1 (0.61) GPR35TDP1ALDH1A1TSHRHPGD
SCHEMBL29939725 0.80 TDP1 (0.61) GPR35TDP1ALDH1A1TSHRHPGD
SCHEMBL8083889 0.80 GPR35 (0.58) GPR35TDP1KDM4EMEN1MAPT
SCHEMBL8082966 0.78 GPR35 (0.56) GPR35TDP1KDM4EMEN1MAPT
SCHEMBL6815361 0.78 GPR35 (0.56) GPR35TDP1KDM4EMEN1MAPT
SCHEMBL10599169 0.78 GPR35 (0.56) GPR35TDP1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118465140-B Rapid detection method for aromatic nitrogen-containing disinfection byproducts in biological tissues 同济大学 2024-11-05 CN disclosed
CN-118465140-A Rapid detection method for aromatic nitrogen-containing disinfection byproducts in biological tissues 同济大学 2024-08-09 CN disclosed