SCHEMBL29940607

SCHEMBL29940607

O=C1OC(OC2CCCCC2)C(Cl)=C1Cl

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 1/20 0.37
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 1/20 0.32
CEL P19835 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29822026 0.71 CYP3A4 (0.31)
SCHEMBL14505730 0.69 KDM4E (0.40) CCKBRKMT2AALDH1A1HIF1AHSD17B10
SCHEMBL14505734 0.64 ALDH1A1 (0.31) KMT2AALDH1A1HSD17B10
SCHEMBL14505732 0.64 KMT2A (0.50) CCKBRKMT2AALDH1A1HIF1AHSD17B10
SCHEMBL14505731 0.64 ALDH1A1 (0.51) CCKBRKMT2AALDH1A1HSD17B10
SCHEMBL6326740 0.62 NSD2 (0.37) CCKBRKMT2AALDH1A1HSD17B10
SCHEMBL14505737 0.61 CCKBR (0.48) CCKBRNPC1ALDH1A1
SCHEMBL6325401 0.61 CYP2C19 (0.31) ALDH1A1
SCHEMBL9066803 0.60 HPGD (0.36) MEN1KMT2AHPGDALDH1A1HIF1A
SCHEMBL9725970 0.60 CA1 (0.41) NPC1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583927-B Thioether compound, and preparation method and application thereof 华南师范大学 2024-07-12 CN disclosed
CN-115583927-A Thioether compound and preparation method and application thereof 华南师范大学 2023-01-10 CN disclosed
CN-109651310-B N-furanone aryl sulfonyl hydrazide derivative and preparation method and application thereof 华南师范大学 2022-07-22 CN disclosed