Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6328326 | 0.80 | SLC6A2 (0.39) | KMT2AMAPTHTT | |
| SCHEMBL6325401 | 0.80 | CYP2C19 (0.31) | ALDH1A1KDM4EPOLB | |
| SCHEMBL9455633 | 0.74 | ALDH1A1 (0.50) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL30104899 | 0.74 | CCKBR (0.38) | CCKBRCTSBTHRBMAPK1MAPT | |
| SCHEMBL29822108 | 0.70 | CTSV (0.36) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL1057155 | 0.67 | ALDH1A1 (0.55) | KMT2AMAPK1MAPTALDH1A1HTT | |
| SCHEMBL30104857 | 0.67 | CTSV (0.33) | CTSVCTSLCTSBCTSHCTSS | |
| SCHEMBL14505731 | 0.65 | ALDH1A1 (0.51) | CCKBRKMT2ATHRBMAPK1MAPT | |
| SCHEMBL14505732 | 0.65 | KMT2A (0.50) | CCKBRKMT2ATHRBMAPK1MAPT | |
| SCHEMBL14505734 | 0.65 | ALDH1A1 (0.31) | KMT2AMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005026141-A2 | PROCESS FOR PREPARATION OF SUBSTITUTED BUTENOLIDES VIA PALLADIUM-FREE ETHERIFICATION AND AMINATION OF MASKED MUCOHALIC ACIDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | claimed |
| US-20050059831-A1 | Preparation of substituted butenolides via palladium-free etherification and amination of masked mucohalic acids | BLAZECKA PETER GARTH (CA) | 2005-03-17 | — | — | US | claimed |
| CN-115583927-B | Thioether compound, and preparation method and application thereof | 华南师范大学 | 2024-07-12 | — | — | CN | disclosed |
| CN-115583927-A | Thioether compound and preparation method and application thereof | 华南师范大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-109651310-B | N-furanone aryl sulfonyl hydrazide derivative and preparation method and application thereof | 华南师范大学 | 2022-07-22 | — | — | CN | disclosed |
| WO-2005026141-A2 | PROCESS FOR PREPARATION OF SUBSTITUTED BUTENOLIDES VIA PALLADIUM-FREE ETHERIFICATION AND AMINATION OF MASKED MUCOHALIC ACIDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |
| US-20050059831-A1 | Preparation of substituted butenolides via palladium-free etherification and amination of masked mucohalic acids | BLAZECKA PETER GARTH (CA) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059831-A1 | Preparation of substituted butenolides via palladium-free etherification and amination of masked mucohalic acids | DBH, OR51E2, OR10J3 | NSD2 1372/4885HSP90AA1 2402/4885HKDC1 4170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.