Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21893246 | 1.00 | ACACB (0.47) | ACACBRAB9ANPC1POLBCA1 | |
| SCHEMBL18262463 | 0.85 | ACE (0.52) | ACACBRAB9ANPC1POLBCTSB | |
| SCHEMBL18262461 | 0.85 | ACE (0.52) | ACACBRAB9ANPC1POLBCTSB | |
| SCHEMBL20415861 | 0.85 | REN (0.46) | ACACBRAB9ANPC1POLBTAS1R3 | |
| SCHEMBL20415717 | 0.84 | CTSC (0.49) | ACACBRAB9ANPC1POLBTAS1R3 | |
| SCHEMBL18262693 | 0.84 | TAS1R3 (0.52) | ACACBRAB9ANPC1POLBTAS1R3 | |
| SCHEMBL20415708 | 0.84 | TAS1R3 (0.52) | ACACBRAB9ANPC1POLBTAS1R3 | |
| SCHEMBL21893206 | 0.81 | CA1 (0.41) | CA1CA2CA7KLK5CA4 | |
| SCHEMBL20397635 | 0.78 | KLK5 (0.46) | TAS1R3TAS1R1KLK5CTSBCTSS | |
| SCHEMBL20415765 | 0.78 | ECE1 (0.40) | ACACBRAB9ANPC1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447498-B2 | Fused tetracyclic compounds and uses thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447498-B2 | Fused tetracyclic compounds and uses thereof in medicine | SLC10A1, CYP4A11, CYP11B2 | ACACB 1501/4885RAB9A 2615/4885NPC1 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.