SCHEMBL29940873

SCHEMBL29940873

C[SiH](c1ccccc1)c1cc([SiH](C)c2ccccc2)cc([SiH](C)c2ccccc2)c1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
ACHE P22303 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4141596 0.92 ACHE (0.32) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL124751 0.91 TSHR (0.39) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL2599044 0.88 TSHR (0.37) LMNATSHRALOX12ACHEALDH1A1
Phosphine SCHEMBL28225524 0.88 TSHR (0.37) LMNATSHRALOX12ACHEALDH1A1
Fluoride SCHEMBL27639907 0.88 TSHR (0.37) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL2522935 0.88 TSHR (0.37) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL23700634 0.80 ALDH1A1 (0.42) ALDH1A1
SCHEMBL12191027 0.78 ACHE (0.50) LMNATSHRALOX12ACHEALDH1A1
SCHEMBL21549242 0.78
SCHEMBL2454182 0.78 ACHE (0.48) LMNATSHRALOX12ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111978542-B Addition-curable silicone composition, cured product, and optical semiconductor element 信越化学工业株式会社 2022-11-11 CN disclosed