SCHEMBL29943809

SCHEMBL29943809

CCOC(=O)c1c(O)c2ccccc2n(O)c1=O

nearest known ligand 0.76

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.76
KDM4E B2RXH2 6/20 0.76
RECQL P46063 1/20 0.70
LMNA P02545 2/20 0.67
HTT P42858 4/20 0.65
NPC1 O15118 1/20 0.54
ALOX15 P16050 1/20 0.54
USP2 O75604 3/20 0.53
HSD17B10 Q99714 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
HPGD P15428 3/20 0.51
GAA P10253 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
TSHR P16473 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27031265 1.00 ALDH1A1 (0.76) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL30099678 0.86 ALDH1A1 (1.00) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL1061607 0.86 ALDH1A1 (1.00) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL2383886 0.85 KDM4E (1.00) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL5308778 0.83 KDM4E (0.77) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL30198068 0.83 KDM4E (0.77) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL5331905 0.83 ALDH1A1 (0.70) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL38660347 0.83 KDM4E (0.86) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL4753992 0.83 RECQL (1.00) ALDH1A1KDM4ERECQLLMNAHTT
SCHEMBL29944198 0.81 KDM4E (0.53) ALDH1A1KDM4ERECQLLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240300899-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF ZYDUS LIFESCIENCES LIMITED (IN) 2024-09-12 US disclosed
EP-4308089-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF Zydus Lifesciences Limited (IN) 2024-01-24 EP disclosed
CN-116997331-A Quinolone compound in solid form and process for preparing same 兹杜斯生命科学有限公司 2023-11-03 CN disclosed
WO-2022195525-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF ZYDUS LIFESCIENCES LIMITED (IN) 2022-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300899-A1 A QUINOLONE COMPOUND IN SOLID FORMS AND PROCESSES FOR THE PREPARATION THEREOF NQO2, SQLE, RECQL ALDH1A1 1319/4885KDM4E 1565/4885RECQL 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.