Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.70 |
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14848286 | 0.90 | ALDH1A1 (0.60) | ALDH1A1KDM4EHTTPOLBRECQL | |
| SCHEMBL29943809 | 0.83 | ALDH1A1 (0.76) | ALDH1A1KDM4EHTTRECQLLMNA | |
| SCHEMBL27031265 | 0.83 | ALDH1A1 (0.76) | ALDH1A1KDM4EHTTRECQLLMNA | |
| SCHEMBL1061607 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EHTTPOLBRECQL | |
| SCHEMBL30099678 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EHTTPOLBRECQL | |
| SCHEMBL30198068 | 0.82 | KDM4E (0.77) | ALDH1A1KDM4EHTTRECQLLMNA | |
| SCHEMBL5308778 | 0.82 | KDM4E (0.77) | ALDH1A1KDM4EHTTRECQLLMNA | |
| SCHEMBL2383886 | 0.82 | KDM4E (1.00) | ALDH1A1KDM4EHTTRECQLLMNA | |
| SCHEMBL38660347 | 0.80 | KDM4E (0.86) | ALDH1A1KDM4EHTTRECQLLMNA | |
| SCHEMBL4753992 | 0.80 | RECQL (1.00) | ALDH1A1KDM4EHTTRECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |