SCHEMBL29944381

SCHEMBL29944381

COc1cc2c(OC)cc1Cc1cc(O)c(cc1O)Cc1cc(OC)c(cc1OC)Cc1cc(OC)c(cc1OC)Cc1cc(OC)c(cc1OC)C2

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.58
MAPT P10636 2/20 0.58
CHRNA7 P36544 1/20 0.43
ACHE P22303 2/20 0.41
MAOB P27338 1/20 0.40
MAOA P21397 6/20 0.40
PTGS2 P35354 1/20 0.40
CYP2D6 P10635 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25591699 0.85 CYP3A4 (0.78) CYP3A4MAPTCHRNA7ACHEMAOB
SCHEMBL29460958 0.85 CYP3A4 (0.78) CYP3A4MAPTCHRNA7ACHEMAOB
Ammonia Solution, Strong SCHEMBL28425365 0.78 CYP3A4 (0.65) CYP3A4MAPTCHRNA7ACHEMAOB
SCHEMBL29441859 0.77 FYN (0.41) CYP3A4MAPTHSD17B10ALDH1A1TSHR
SCHEMBL29394312 0.75 CYP3A4 (1.00) CYP3A4MAPTCHRNA7ACHEMAOB
SCHEMBL4571013 0.75 CYP3A4 (1.00) CYP3A4MAPTCHRNA7ACHEMAOB
SCHEMBL22953335 0.75 CYP3A4 (1.00) CYP3A4MAPTCHRNA7ACHEMAOB
SCHEMBL2138785 0.75 CYP3A4 (1.00) CYP3A4MAPTCHRNA7ACHEMAOB
SCHEMBL23026215 0.73 CYP3A4 (0.58) CYP3A4MAPTCHRNA7MAOBMAOA
SCHEMBL16844830 0.72 ACHE (0.53) CYP3A4MAPTCHRNA7ACHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4467974-A1 NOVEL CHEMOSENSORS AND THEIR USE IN ELECTROCHEMICAL DETECTION METHODS Karlsruher Institut für Technologie (DE) 2024-11-27 EP disclosed
WO-2022196614-A1 AGENT FOR TREATING OR PREVENTING CHAGAS DISEASE 国立大学法人 長崎大学 2022-09-22 WO disclosed