Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20269738 | 1.00 | POLL (0.48) | POLLCYP1A2ADRA1AS1PR1S1PR2 | |
| SCHEMBL13616708 | 0.81 | POLL (0.49) | POLLADRA1ADRD2KDM4E | |
| SCHEMBL6804047 | 0.79 | POLL (0.62) | POLLCYP1A2ADRA1ADRD2DRD3 | |
| SCHEMBL1508668 | 0.79 | POLL (0.62) | POLLCYP1A2ADRA1ADRD2DRD3 | |
| SCHEMBL29660414 | 0.74 | MAP3K14 (0.34) | POLLS1PR1S1PR2S1PR4S1PR3 | |
| SCHEMBL15287132 | 0.74 | MAP3K14 (0.34) | POLLS1PR1S1PR2S1PR4S1PR3 | |
| SCHEMBL35211487 | 0.74 | CYP11B1 (0.37) | POLLS1PR1S1PR2S1PR4S1PR3 | |
| SCHEMBL15287108 | 0.74 | CYP11B1 (0.37) | POLLS1PR1S1PR2S1PR4S1PR3 | |
| SCHEMBL15021555 | 0.74 | CYP11B1 (0.37) | POLLS1PR1S1PR2S1PR4S1PR3 | |
| SCHEMBL10836637 | 0.73 | ADRA1A (0.35) | CYP1A2ADRA1ADRD2DRD3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110049984-B | Phenylpropionic acid derivatives and use thereof | 日东制药株式会社 | 2022-11-15 | — | — | CN | disclosed |