Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831139 | 1.00 | LMNA (0.33) | LMNACYP3A4TDP1GPR84TP53 | |
| SCHEMBL499140 | 1.00 | LMNA (0.33) | LMNACYP3A4TDP1GPR84TP53 | |
| Hydrochloric Acid SCHEMBL9819186 | 0.98 | LMNA (0.32) | LMNACYP3A4TDP1GPR84 | |
| Hydrochloric Acid SCHEMBL3144275 | 0.96 | LMNA (0.31) | LMNACYP3A4TDP1 | |
| SCHEMBL29578359 | 0.93 | — | — | |
| SCHEMBL5391459 | 0.93 | — | — | |
| SCHEMBL6569406 | 0.85 | LMNA (0.39) | LMNACYP3A4TDP1GPR84TP53 | |
| SCHEMBL4402575 | 0.85 | AOC3 (0.32) | CYP3A4TDP1GPR84 | |
| SCHEMBL4401377 | 0.82 | PCSK9 (0.33) | — | |
| SCHEMBL11789090 | 0.82 | CYP3A4 (0.33) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293938-B2 | Alkylphosphonous acids, salts and esters, methods for the production thereof, and use of the same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-10-23 | — | — | US | disclosed |
| US-20100190901-A1 | Alkylphosphonous Acids, Salts and Esters, Methods for the Production Thereof, and Use of the Same | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-07-29 | — | — | US | disclosed |