SCHEMBL499140

SCHEMBL499140

CCC(CP(c1ccccc1)c1ccccc1)P(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GPR84 Q9NQS5 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2831139 1.00 LMNA (0.33) LMNACYP3A4TDP1GPR84TP53
SCHEMBL2994488 1.00 LMNA (0.33) LMNACYP3A4TDP1GPR84TP53
Hydrochloric Acid SCHEMBL9819186 0.98 LMNA (0.32) LMNACYP3A4TDP1GPR84
Hydrochloric Acid SCHEMBL3144275 0.96 LMNA (0.31) LMNACYP3A4TDP1
SCHEMBL29578359 0.93
SCHEMBL5391459 0.93
SCHEMBL6569406 0.85 LMNA (0.39) LMNACYP3A4TDP1GPR84TP53
SCHEMBL4402575 0.85 AOC3 (0.32) CYP3A4TDP1GPR84
SCHEMBL4401377 0.82 PCSK9 (0.33)
SCHEMBL11789090 0.82 CYP3A4 (0.33) CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427468-B2 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2025-06-04 EP claimed
EP-4267591-A2 ORGANOMETALLIC COMPOUNDS Umicore AG & Co. KG (DE) 2023-11-01 EP claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN claimed
CN-115957823-A Ethylene carbonylation catalyst and application thereof 上海浦景化工技术股份有限公司 2023-04-14 CN claimed
CN-115403465-A Preparation method for synthesizing organic carboxylic ester from carbon dioxide and olefin 湖南工程学院 2022-11-29 CN claimed
CN-115304441-A Preparation method for synthesizing amide from carbon dioxide and olefin 湖南工程学院 2022-11-08 CN claimed
CN-114989031-A Preparation method for synthesizing unsaturated amide from carbon dioxide and alkyne 湖南工程学院 2022-09-02 CN claimed
CN-114957012-A Preparation method for synthesizing unsaturated organic carboxylic ester by carbon dioxide and alkyne 湖南工程学院 2022-08-30 CN claimed
WO-2022136049-A2 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2022-06-30 WO claimed
EP-2427468-B1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2017-06-14 EP claimed
US-20160046607-A1 METHOD FOR PRODUCING SUBSTITUTED ANTHRANILIC ACID DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-02-18 US claimed
EP-2683686-B1 METHOD FOR THE PREPARATION OF PRIMARY AMINES BY HOMOGENEOUS CATALYSED AMINATION OF ALCOHOLS BASF SE (DE) 2015-05-13 EP claimed
US-20150011772-A1 METHOD FOR PRODUCING SUBSTITUTED ANTHRANILIC ACID DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-01-08 US claimed
US-8785693-B2 Process for the preparation of primary amines by homogeneously catalyzed alcohol amination BASF SE (DE) 2014-07-22 US claimed
US-8772520-B2 Preparation of a metal complex JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2014-07-08 US claimed
CN-103502212-A Method for producing primary amines obtained by homogeneously catalyzed alcohol amination BASF SE 2014-01-08 CN claimed
US-20120232292-A1 PROCESS FOR THE PREPARATION OF PRIMARY AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION BASF SE (DE) 2012-09-13 US claimed
US-20120116109-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-05-10 US claimed
EP-1107939-B1 PHOSPHINE LIGAND PROMOTED SYNTHESIS OF TETRAARYLOXYALKANE AND DIARYLCARBONATES GEN ELECTRIC (US) 2003-08-06 EP claimed
US-4496766-A FROM AN A-DISUBSTITUTED-8-KETO ACID ESTER; USING A CATALYST COMPLEX OF A PALLADIUM COMPOUND AND A PHOSPHINE NIPPON ZEON CO. LTD. (JP) 1985-01-29 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120232292-A1 PROCESS FOR THE PREPARATION OF PRIMARY AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION ADH1A, ADH1C, ADH5 LMNA 2646/4885CYP3A4 806/4885TDP1 2390/4885
US-20160046607-A1 METHOD FOR PRODUCING SUBSTITUTED ANTHRANILIC ACID DERIVATIVES NQO2, PAH, ANTXR2 LMNA 3769/4885CYP3A4 85/4885TDP1 4307/4885
US-20150011772-A1 METHOD FOR PRODUCING SUBSTITUTED ANTHRANILIC ACID DERIVATIVES NQO2, PAH, ANTXR2 LMNA 3769/4885CYP3A4 85/4885TDP1 4307/4885
US-20120116109-A1 PREPARATION OF A METAL COMPLEX PDCD1LG2, CD274, PDCD2L LMNA 668/4885CYP3A4 4024/4885TDP1 2302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.