Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | UBE2N | P61088 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944814 | 0.90 | ROCK2 (0.64) | ROCK2MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL29944815 | 0.84 | MEN1 (0.81) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL4026426 | 0.83 | MEN1 (0.61) | ROCK2MEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL22664681 | 0.82 | HDAC1 (0.69) | MEN1KMT2AALDH1A1LMNANR1H4 | |
| SCHEMBL28859140 | 0.82 | NR1H4 (0.82) | ROCK2ALDH1A1LMNANR1H4NPC1 | |
| SCHEMBL4141962 | 0.80 | MEN1 (0.89) | MEN1KMT2ACYP3A4ALDH1A1LMNA | |
| SCHEMBL307847 | 0.79 | ROCK2 (0.84) | ROCK2MEN1KMT2ACYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9638131 | 0.79 | MEN1 (0.86) | MEN1KMT2ACYP3A4ALDH1A1LMNA | |
| SCHEMBL22664696 | 0.79 | MEN1 (0.74) | MEN1KMT2AALDH1A1LMNANR1H4 | |
| SCHEMBL8813394 | 0.78 | MEN1 (0.58) | MEN1KMT2AALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479536-B1 | Arylacetamides as AMP-activated protein kinase inhibitors and their use for treatment of breast cancer | KING ABDULAZIZ UNIVERSITY (SA) | 2022-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11479536-B1 | Arylacetamides as AMP-activated protein kinase inhibitors and their use for treatment of breast cancer | PRKAA2, PRKAA1, PRKAG2 | ROCK2 1144/4885MEN1 3759/4885KMT2A 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.