SCHEMBL29944964

SCHEMBL29944964

CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.61
OPRD1 P41143 2/20 0.59
OPRK1 P41145 1/20 0.59
SLC6A2 P23975 1/20 0.57
LTA4H P09960 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29710134 0.92 SLC6A2 (0.59) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL3817152 0.91 OPRM1 (0.61) OPRM1OPRD1OPRK1
SCHEMBL29702054 0.91 OPRM1 (0.66) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL31412199 0.91 OPRM1 (0.66) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL30833622 0.91 OPRM1 (0.66) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL3812839 0.90 OPRM1 (0.62) OPRM1OPRD1OPRK1
SCHEMBL31553199 0.90 SLC6A2 (0.60) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL30060726 0.90 OPRM1 (0.69) OPRM1OPRD1OPRK1SLC6A2
SCHEMBL30576724 0.89 OPRM1 (0.62) OPRM1OPRD1OPRK1
SCHEMBL10302843 0.88 SLC6A2 (0.60) OPRM1OPRD1OPRK1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
CN-113173970-B Walnut meal anti-inflammatory peptide FPL and application thereof 北京林业大学 2022-11-15 CN disclosed
CN-113173970-B Walnut meal anti-inflammatory peptide FPL and application thereof 北京林业大学 2022-11-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP OPRM1 804/4885OPRD1 402/4885OPRK1 2117/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD OPRM1 2130/4885OPRD1 2937/4885OPRK1 2437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.