Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944964 | 0.90 | OPRM1 (0.61) | OPRM1OPRD1OPRK1 | |
| Acetic Acid SCHEMBL11289266 | 0.88 | OPRM1 (0.69) | OPRM1OPRD1OPRK1 | |
| SCHEMBL30157193 | 0.88 | OPRM1 (0.73) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3817152 | 0.88 | OPRM1 (0.61) | OPRM1OPRD1OPRK1 | |
| SCHEMBL11289268 | 0.86 | OPRM1 (0.66) | OPRM1OPRD1OPRK1 | |
| SCHEMBL29710134 | 0.84 | SLC6A2 (0.59) | OPRM1OPRD1OPRK1 | |
| SCHEMBL38658663 | 0.83 | OPRM1 (0.78) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13594465 | 0.83 | PSMB9 (0.54) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3635117 | 0.83 | OPRM1 (0.67) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14401583 | 0.83 | OPRM1 (0.53) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086993-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | Zedira GmbH (DE) | 2009-08-12 | — | — | EP | claimed |
| WO-2008055488-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | ZEDIRA GMBH (DE) | 2008-05-15 | — | — | WO | claimed |
| EP-2086993-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | Zedira GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008055488-A1 | MICHAEL SYSTEMS AS TRANSGLUTAMINASE INHIBITORS | ZEDIRA GMBH (DE) | 2008-05-15 | — | — | WO | disclosed |