SCHEMBL29945583

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	1/20	0.42

▸	APLNR	P35414	1/20	0.40

▸	KMT2A	Q03164	1/20	0.40

▸	NAA50	Q9GZZ1	1/20	0.40

▸	NTSR1	P30989	3/20	0.39

▸	NMUR2	Q9GZQ4	2/20	0.39

▸	NMUR1	Q9HB89	2/20	0.39

▸	OPRD1	P41143	2/20	0.38

▸	OPRM1	P35372	1/20	0.38

▸	MMP3	P08254	2/20	0.37

▸	CAPN1	P07384	2/20	0.37

▸	PSMB9	P28065	2/20	0.37

▸	NTSR2	O95665	1/20	0.37

▸	MMP1	P03956	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30483724	0.91	REN (0.44)	RENAPLNRKMT2ANAA50NTSR1
SCHEMBL29407478	0.91	REN (0.44)	RENAPLNRKMT2ANAA50NTSR1
SCHEMBL30099417	0.90	REN (0.41)	RENAPLNRKMT2ANAA50NTSR1
SCHEMBL30430384	0.88	OPRM1 (0.45)	RENAPLNRKMT2ANAA50NTSR1
SCHEMBL30099452	0.87	KMT2A (0.40)	RENAPLNRKMT2ANAA50NTSR1
SCHEMBL30099624	0.87	REN (0.42)	RENAPLNRKMT2ANAA50NTSR1
SCHEMBL29485040	0.86	PREP (0.39)	RENAPLNRKMT2APSMB9
SCHEMBL31419720	0.86	APLNR (0.44)	RENAPLNRKMT2ANAA50NTSR1
SCHEMBL30468684	0.85	APLNR (0.43)	RENAPLNRKMT2ANAA50MMP3
SCHEMBL31622294	0.84	REN (0.44)	RENAPLNRKMT2ANAA50NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110755629-B	Step-by-step response type double-gene delivery system and preparation method thereof	天津大学	2022-09-23	—	—	CN	disclosed