SCHEMBL29945748 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	TRPA1	O75762	1/20	0.41

▸	AAK1	Q2M2I8	7/20	0.40

▸	CTSS	P25774	3/20	0.37

▸	CTSK	P43235	3/20	0.37

▸	KMT2A	Q03164	2/20	0.37

▸	TSHR	P16473	1/20	0.36

▸	HSD17B10	Q99714	1/20	0.36

▸	CA1	P00915	1/20	0.35

▸	CA2	P00918	1/20	0.35

▸	CA7	P43166	1/20	0.35

▸	MEN1	O00255	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28880364	1.00	TRPA1 (0.41)	TRPA1AAK1CTSSCTSKKMT2A
SCHEMBL26464327	1.00	TRPA1 (0.41)	TRPA1AAK1CTSSCTSKKMT2A
SCHEMBL30493109	0.88	TRPA1 (0.42)	TRPA1AAK1CTSSCTSKKMT2A
SCHEMBL25843190	0.86	TRPA1 (0.38)	TRPA1AAK1CTSSCTSKCA1
SCHEMBL1345706	0.83	GPR139 (0.43)	TRPA1AAK1CTSSCTSKKMT2A
SCHEMBL1345707	0.83	GPR139 (0.43)	TRPA1AAK1CTSSCTSKKMT2A
SCHEMBL23526471	0.82	LMNA (0.36)	KMT2AMEN1
SCHEMBL30013870	0.82	LMNA (0.36)	KMT2AMEN1
SCHEMBL23526468	0.82	LMNA (0.36)	KMT2AMEN1
SCHEMBL30502604	0.81	TRPA1 (0.52)	TRPA1AAK1CTSSCTSKKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115135315-A	SOS1 inhibitors	米拉蒂治疗股份有限公司	2022-09-30	—	—	CN	disclosed