Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857450 | 1.00 | ENPP1 (0.44) | ENPP1AURKAALDH1A1MAPTMEN1 | |
| SCHEMBL29945735 | 0.89 | KDM4E (0.42) | ENPP1AURKAALDH1A1MAPTMEN1 | |
| SCHEMBL23526128 | 0.89 | KDM4E (0.42) | ENPP1AURKAALDH1A1MAPTMEN1 | |
| SCHEMBL29945835 | 0.83 | PDE5A (0.38) | ENPP1AURKAALDH1A1MAPTMEN1 | |
| SCHEMBL23526090 | 0.83 | PDE5A (0.38) | ENPP1AURKAALDH1A1MAPTMEN1 | |
| SCHEMBL3062053 | 0.78 | ALDH1A1 (0.55) | ENPP1AURKAALDH1A1PGK1SMN1; SMN2 | |
| SCHEMBL29945866 | 0.78 | ALDH1A1 (0.55) | ENPP1AURKAALDH1A1PGK1SMN1; SMN2 | |
| SCHEMBL6588404 | 0.77 | FLT1 (0.53) | ALDH1A1MEN1KMT2APDE3APDE3B | |
| SCHEMBL8421521 | 0.75 | NQO1 (0.48) | ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6590560 | 0.74 | PDE4A (0.64) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115515939-B | Novel phthalazine derivatives having activity of inhibiting exonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115515939-A | Novel phthalazine derivatives having an inhibitory activity on ectonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |