Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062053 | 1.00 | ALDH1A1 (0.55) | ALDH1A1FLT1EGFRSOS1PDE4A | |
| SCHEMBL4157998 | 0.81 | ALDH1A1 (0.55) | ALDH1A1FLT1EGFRSOS1PDE4A | |
| SCHEMBL13815416 | 0.80 | FLT1 (0.43) | FLT1EGFRKDRENPP1 | |
| SCHEMBL31678471 | 0.79 | ALDH1A1 (0.57) | ALDH1A1FLT1EGFRSOS1KDM4E | |
| SCHEMBL29945742 | 0.78 | ALDH1A1 (0.55) | ALDH1A1FLT1EGFRSOS1PDE4A | |
| SCHEMBL29945847 | 0.78 | ENPP1 (0.44) | ALDH1A1KDM4ESMN1; SMN2PDE10APGK1 | |
| SCHEMBL8857450 | 0.78 | ENPP1 (0.44) | ALDH1A1KDM4ESMN1; SMN2PDE10APGK1 | |
| SCHEMBL23709204 | 0.75 | SOS1 (0.52) | ALDH1A1FLT1EGFRSOS1PDE4A | |
| SCHEMBL1526862 | 0.75 | MTNR1A (0.49) | ALDH1A1EGFRKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL23709202 | 0.75 | ALDH1A1 (0.52) | ALDH1A1FLT1EGFRSOS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462626-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119233820-A | Azo compounds for the treatment of fibrotic diseases | 乔治-奥古斯特-哥廷根公法基金会大学的大学医学院 | 2024-12-31 | — | — | CN | disclosed |
| CN-115135315-B | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-115135315-A | SOS1 inhibitors | 米拉蒂治疗股份有限公司 | 2022-09-30 | — | — | CN | disclosed |