Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945820 | 0.87 | MAPT (0.46) | GPR119MAPTSMN1; SMN2DPP4 | |
| SCHEMBL24265672 | 0.84 | GPR119 (0.49) | GPR119DPP4IRAK4 | |
| SCHEMBL29574130 | 0.84 | GPR119 (0.49) | GPR119DPP4IRAK4 | |
| SCHEMBL29945963 | 0.82 | GPR119 (0.49) | GPR119MAPTSMN1; SMN2DPP4IRAK4 | |
| SCHEMBL29946004 | 0.81 | CTSB (0.39) | MAPTSMN1; SMN2 | |
| SCHEMBL24266550 | 0.79 | GPR119 (0.49) | GPR119DPP4IRAK4 | |
| SCHEMBL29573860 | 0.79 | GPR119 (0.49) | GPR119DPP4IRAK4 | |
| SCHEMBL29573807 | 0.78 | GPR119 (0.49) | GPR119IRAK4 | |
| SCHEMBL26484114 | 0.78 | GPR119 (0.49) | GPR119IRAK4 | |
| SCHEMBL24265675 | 0.78 | GPR119 (0.50) | GPR119IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |