Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | MPO | P05164 | 4/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945844 | 0.85 | INPPL1 (0.37) | SLC6A2SLC6A4SLC6A3JAK2RAB9A | |
| SCHEMBL29945889 | 0.81 | GPR119 (0.47) | MAPTSMN1; SMN2 | |
| SCHEMBL29945912 | 0.79 | KDM1A (0.39) | KDM1ASLC6A2SLC6A4SLC6A3JAK2 | |
| SCHEMBL29945923 | 0.77 | MEN1 (0.40) | CTSBKDM1AMPOHSD11B1SLC6A2 | |
| SCHEMBL24266549 | 0.72 | HTR6 (0.41) | KDM1ASLC6A2SLC6A4SLC6A3JAK2 | |
| SCHEMBL24265507 | 0.71 | HTR6 (0.46) | KDM1ASLC6A2SLC6A4SLC6A3JAK2 | |
| SCHEMBL29573778 | 0.71 | HTR6 (0.46) | KDM1ASLC6A2SLC6A4SLC6A3JAK2 | |
| SCHEMBL24265686 | 0.71 | KDM1A (0.44) | KDM1ASLC6A2SLC6A4SLC6A3JAK2 | |
| SCHEMBL29574126 | 0.71 | KDM1A (0.44) | KDM1ASLC6A2SLC6A4SLC6A3JAK2 | |
| SCHEMBL24265925 | 0.70 | INPPL1 (0.40) | KDM1ASLC6A2SLC6A4SLC6A3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |