Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945891 | 0.91 | DRD2 (0.41) | DRD2TBXA2RACSS2LCKKDM4E | |
| SCHEMBL20266537 | 0.86 | GLP1R (0.45) | DRD2TBXA2RACSS2LCKKDM4E | |
| SCHEMBL31159736 | 0.86 | GLP1R (0.45) | DRD2TBXA2RACSS2LCKKDM4E | |
| Hydrochloric Acid SCHEMBL30269640 | 0.85 | GLP1R (0.44) | DRD2TBXA2RACSS2LCKKDM4E | |
| Hydrochloric Acid SCHEMBL28910361 | 0.85 | GLP1R (0.44) | DRD2TBXA2RACSS2LCKKDM4E | |
| SCHEMBL24265338 | 0.85 | ACSS2 (0.46) | DRD2TBXA2RACSS2LCKKDM4E | |
| SCHEMBL30740718 | 0.85 | ACSS2 (0.46) | DRD2TBXA2RACSS2LCKKDM4E | |
| SCHEMBL29945993 | 0.83 | ACSS2 (0.41) | DRD2TBXA2RACSS2LCKKDM4E | |
| SCHEMBL30686438 | 0.81 | GLP1R (0.41) | DRD2TBXA2RACSS2LCKGLP1R | |
| SCHEMBL27111057 | 0.81 | GLP1R (0.41) | DRD2TBXA2RACSS2LCKGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184849-A1 | GLP-1R AGONISTS, USES AND PHARMACEUTICAL COMPOSITIONS THEREOF | LES LABORATOIRES SERVIER (FR) | 2022-09-09 | — | — | WO | disclosed |