Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13261222 | 0.77 | CYP19A1 (0.53) | LMNATSHRCYP19A1 | |
| SCHEMBL178322 | 0.77 | CYP19A1 (0.53) | LMNATSHRCYP19A1 | |
| SCHEMBL103226 | 0.77 | CYP19A1 (0.53) | LMNATSHRCYP19A1 | |
| SCHEMBL13979324 | 0.75 | CYP19A1 (0.51) | LMNATSHRCYP19A1 | |
| SCHEMBL9144444 | 0.75 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL8599269 | 0.74 | KMT2A (0.32) | CYP19A1 | |
| SCHEMBL11800559 | 0.70 | CYP19A1 (0.46) | LMNATSHRCYP19A1 | |
| SCHEMBL19170565 | 0.69 | GRIN1 (0.31) | — | |
| SCHEMBL8817772 | 0.69 | CYP19A1 (0.72) | LMNATSHRCYP19A1 | |
| SCHEMBL21442483 | 0.69 | CYP19A1 (0.72) | LMNATSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306645-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | TARO PHARMACEUTICALS INC. (CA) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306645-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | IL1B, IL1A, LTB4R | LMNA 2184/4885TSHR 2622/4885CYP19A1 352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.