Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877316 | 0.81 | ADORA2A (0.43) | NPC1RAB9AADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL29947885 | 0.79 | MKNK1 (0.47) | NPC1MAPK14MAOB | |
| SCHEMBL28877251 | 0.74 | ALOX15 (0.40) | NPC1RAB9AADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL28877263 | 0.71 | KDM4E (0.40) | NPC1RAB9AADORA2AADORA1ADORA2B | |
| SCHEMBL29947774 | 0.70 | ADORA1 (0.40) | ADORA2AADORA1MAPK14ALDH1A1HSD17B10 | |
| SCHEMBL29947735 | 0.69 | GP6 (0.41) | ADORA2AADORA1ADORA2B | |
| SCHEMBL29947798 | 0.68 | ADORA2A (0.40) | ADORA2AADORA1ADORA2BMAPT | |
| SCHEMBL13108724 | 0.68 | MAPT (0.56) | NPC1RAB9AADORA2AADORA1ADORA2B | |
| SCHEMBL4148219 | 0.67 | PDE3B (0.47) | NPC1RAB9AMAPK14MAPK10ERBB2 | |
| SCHEMBL11714829 | 0.67 | ADORA2A (0.47) | NPC1RAB9AADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |