Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947737 | 0.87 | RXRA (0.41) | ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL378833 | 0.69 | ALDH1A1 (0.36) | — | |
| SCHEMBL17563220 | 0.69 | ALDH1A1 (0.36) | ENPP3ENPP1 | |
| SCHEMBL29947692 | 0.68 | NPC1 (0.43) | ADORA2AADORA1MAPTADORA2B | |
| SCHEMBL28877316 | 0.68 | ADORA2A (0.43) | ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL4463336 | 0.64 | HEXA (0.47) | ADORA2AADORA1ADORA2B | |
| SCHEMBL22969334 | 0.64 | ADORA2A (0.46) | ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL15051818 | 0.64 | LMNA (0.48) | ADORA2AADORA1KDM4EMAPT | |
| SCHEMBL2531545 | 0.63 | ALDH1A1 (0.53) | — | |
| SCHEMBL13232020 | 0.62 | ACHE (0.33) | ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |