SCHEMBL29947667

SCHEMBL29947667

CC(C)C[C@H](NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ EED O75530 2/20 0.41
▸ PRCP P42785 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ DPP7 Q9UHL4 1/20 0.40
▸ REN P00797 4/20 0.40
▸ NTSR2 O95665 1/20 0.39
▸ GHSR Q92847 1/20 0.38
▸ MAPK8 P45983 1/20 0.38
▸ MAPK9 P45984 1/20 0.38
▸ MAPK10 P53779 1/20 0.38
▸ CTSL P07711 1/20 0.38
▸ CTSB P07858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437943 0.92 MAPK8 (0.43) EEDPRCPMEN1KMT2AMAPK8
SCHEMBL30193521 0.92 MEN1 (0.45) PRCPMEN1KMT2ADPP7GHSR
SCHEMBL29947814 0.89 PRCP (0.44) PRCPMEN1KMT2ADPP7REN
SCHEMBL8720817 0.88 MAPK8 (0.44) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL8720811 0.88 MAPK8 (0.44) PRCPMEN1KMT2AMAPK8MAPK9
SCHEMBL29663559 0.88 MAPK8 (0.46) PRCPMAPK8MAPK9MAPK10
SCHEMBL31572023 0.87 MEN1 (0.48) PRCPMEN1KMT2ADPP7
SCHEMBL30193311 0.87 MEN1 (0.42) PRCPMEN1KMT2ADPP7
SCHEMBL30193219 0.87 MEN1 (0.42) PRCPMEN1KMT2ADPP7
SCHEMBL30193454 0.87 PRCP (0.44) PRCPMEN1KMT2ADPP7MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP claimed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US claimed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP claimed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO claimed
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 — — EP disclosed
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2024-06-13 — — US disclosed
EP-4301417-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES The Research Foundation for The State University of New York (US) 2024-01-10 — — EP disclosed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189440-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES TLR7, TLR8, TLR9 EED 4143/4885PRCP 1840/4885MEN1 4422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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