Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 7/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | RRM1 | P23921 | 4/20 | 0.34 |
| ▸ | RRM2B | Q7LG56 | 4/20 | 0.34 |
| ▸ | IL2 | P60568 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529308 | 1.00 | NOTUM (0.40) | NOTUMPARP1PKN1PKN2CHRM2 | |
| SCHEMBL23529337 | 0.89 | PTGER4 (0.33) | NOTUMPARP1PKN1PKN2CHRM2 | |
| SCHEMBL29948206 | 0.89 | PTGER4 (0.33) | NOTUMPARP1PKN1PKN2CHRM2 | |
| SCHEMBL29948192 | 0.89 | RRM1 (0.36) | NOTUMCHRM2CHRM1RRM1RRM2B | |
| SCHEMBL23529326 | 0.89 | RRM1 (0.36) | NOTUMCHRM2CHRM1RRM1RRM2B | |
| SCHEMBL24800770 | 0.83 | POLQ (0.37) | PARP1PKN1PKN2PTGER4TYK2 | |
| SCHEMBL30159523 | 0.83 | POLQ (0.37) | PARP1PKN1PKN2PTGER4TYK2 | |
| SCHEMBL24801182 | 0.82 | TYK2 (0.38) | PARP1PKN1PKN2PTGER4TYK2 | |
| SCHEMBL30159588 | 0.82 | TYK2 (0.38) | PARP1PKN1PKN2PTGER4TYK2 | |
| SCHEMBL23529304 | 0.81 | ACSS2 (0.39) | PARP1PKN1PKN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077318-B1 | BENZIMIDAZOLE DIMERS AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2025-10-15 | — | — | EP | claimed |
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | claimed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | claimed |
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2022266711-A1 | SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS | Aculeus Therapeutics Pty Ltd (AU) | 2022-12-29 | — | — | WO | disclosed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | disclosed |