Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 18/20 | 0.36 |
| ▸ | RRM2B | Q7LG56 | 18/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 17/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529326 | 1.00 | RRM1 (0.36) | RRM1RRM2BCHRM2CHRM1NOTUM | |
| SCHEMBL23529337 | 0.93 | PTGER4 (0.33) | RRM1RRM2BCHRM2CHRM1NOTUM | |
| SCHEMBL29948206 | 0.93 | PTGER4 (0.33) | RRM1RRM2BCHRM2CHRM1NOTUM | |
| SCHEMBL29948137 | 0.89 | NOTUM (0.40) | RRM1RRM2BCHRM2CHRM1NOTUM | |
| SCHEMBL23529308 | 0.89 | NOTUM (0.40) | RRM1RRM2BCHRM2CHRM1NOTUM | |
| SCHEMBL24801625 | 0.88 | NOTUM (0.44) | RRM1RRM2BCHRM2CHRM1NOTUM | |
| SCHEMBL29948143 | 0.88 | NOTUM (0.44) | RRM1RRM2BCHRM2CHRM1NOTUM | |
| SCHEMBL23552398 | 0.84 | PTGER4 (0.41) | — | |
| SCHEMBL29948164 | 0.84 | PTGER4 (0.41) | — | |
| SCHEMBL23529396 | 0.82 | GPR35 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077318-B1 | BENZIMIDAZOLE DIMERS AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2025-10-15 | — | — | EP | claimed |
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | claimed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | claimed |
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2022266711-A1 | SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS | Aculeus Therapeutics Pty Ltd (AU) | 2022-12-29 | — | — | WO | disclosed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | disclosed |