Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 5/20 | 0.45 |
| ▸ | CES1 | P23141 | 5/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529377 | 1.00 | ERN1 (0.47) | ERN1CES2CES1KEAP1KDM4E | |
| SCHEMBL30159547 | 0.81 | AKR1C4 (0.44) | ERN1KEAP1ALDH1A1CA1CA2 | |
| SCHEMBL23529330 | 0.81 | AKR1C4 (0.44) | ERN1KEAP1ALDH1A1CA1CA2 | |
| SCHEMBL95723 | 0.78 | ERN1 (0.50) | ERN1CES2CES1ALDH1A1MEN1 | |
| SCHEMBL1421628 | 0.74 | CES2 (0.71) | ERN1CES2CES1KEAP1KDM4E | |
| SCHEMBL8466122 | 0.72 | CES2 (0.50) | ERN1CES2CES1KEAP1KDM4E | |
| SCHEMBL29695966 | 0.72 | AKR1C2 (0.58) | ERN1CES2CES1KEAP1KDM4E | |
| SCHEMBL2791251 | 0.72 | AKR1C2 (0.58) | ERN1CES2CES1KEAP1KDM4E | |
| SCHEMBL3967319 | 0.72 | ERN1 (0.52) | ERN1CES2CES1KDM4ECA1 | |
| SCHEMBL1813635 | 0.72 | LMNA (0.44) | ERN1CES2CES1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | disclosed |
| CN-114981265-A | Compound (I) | CTXT私人有限公司 | 2022-08-30 | — | — | CN | disclosed |