Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 6/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | TPO | P07202 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23552642 | 1.00 | IDO1 (0.41) | IDO1PTGER4AAK1JAK2PKN1 | |
| SCHEMBL30159379 | 0.85 | ROCK2 (0.39) | PTGER4AAK1PKN1PKN2 | |
| SCHEMBL24802713 | 0.85 | ROCK2 (0.39) | PTGER4AAK1PKN1PKN2 | |
| SCHEMBL23529335 | 0.84 | XDH (0.39) | IDO1PTGER4 | |
| SCHEMBL23529388 | 0.82 | IDO1 (0.39) | IDO1PTGER4 | |
| SCHEMBL23529315 | 0.82 | PTGER4 (0.47) | PTGER4PKN1PKN2IDH1 | |
| SCHEMBL23529300 | 0.82 | PTGER4 (0.47) | PTGER4PKN1PKN2IDH1 | |
| SCHEMBL25095233 | 0.81 | ABL1 (0.43) | PTGER4JAK2PKN1PKN2IDH1 | |
| SCHEMBL23530087 | 0.81 | ABL1 (0.41) | PTGER4PKN1PKN2IDH1SYK | |
| SCHEMBL29948211 | 0.81 | ABL1 (0.43) | PTGER4JAK2PKN1PKN2IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077318-B1 | BENZIMIDAZOLE DIMERS AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2025-10-15 | — | — | EP | claimed |
| CN-114981265-B | Compounds of formula (I) | CTXT私人有限公司 | 2025-01-03 | — | — | CN | claimed |
| EP-4077318-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2022-10-26 | — | — | EP | claimed |
| US-20260132112-A1 | COMPOUNDS | CTXT PTY LTD (AU) | 2026-05-14 | — | — | US | disclosed |
| US-12415785-B2 | Compound modulators of sting | CTXT PTY LTD (AU) | 2025-09-16 | — | — | US | disclosed |
| US-20230062932-A1 | COMPOUNDS | CTXT PTY LTD. (AU) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12415785-B2 | Compound modulators of sting | STING1, IRF3, MAVS | IDO1 1650/4885PTGER4 2061/4885AAK1 1881/4885 |
| US-20260132112-A1 | COMPOUNDS | STING1, IRF3, CGAS | IDO1 442/4885PTGER4 1426/4885AAK1 3910/4885 |
| US-20230062932-A1 | COMPOUNDS | STING1, IRF3, MAVS | IDO1 1177/4885PTGER4 1526/4885AAK1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.