SCHEMBL29948252

SCHEMBL29948252

O=C(O)c1ccc(C(c2ccc(C(=O)C(O)c3ccccc3)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.58
CES1 P23141 3/20 0.58
LMNA P02545 3/20 0.57
ALDH1A1 P00352 2/20 0.50
KDM4E B2RXH2 1/20 0.50
PTPN1 P18031 2/20 0.43
TSHR P16473 2/20 0.43
HSD17B10 Q99714 1/20 0.43
SRD5A2 P31213 4/20 0.42
MAPK1 P28482 1/20 0.41
PDPK1 O15530 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GSK3B P49841 1/20 0.38
DAO P14920 1/20 0.37
NAPRT Q6XQN6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290961 0.82 SRD5A2 (0.55) CES2CES1PTPN1TSHRSRD5A2
Benzoin SCHEMBL343010 0.81 CES2 (0.88) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL336470 0.80 SRD5A2 (0.61) CES2CES1ALDH1A1TSHRSRD5A2
SCHEMBL17894698 0.80 CES2 (0.63) CES2CES1LMNAALDH1A1KDM4E
Hydrochloric Acid SCHEMBL8505603 0.79 SRD5A2 (0.59) CES2CES1ALDH1A1TSHRSRD5A2
Hydrochloric Acid SCHEMBL19837805 0.79 SRD5A2 (0.59) CES2CES1ALDH1A1TSHRSRD5A2
SCHEMBL5445265 0.76 CES2 (0.83) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL4331474 0.76 ALDH1A1 (0.68) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL9742053 0.76 RXRA (0.59) LMNAKDM4ETSHRHSD17B10SRD5A2
SCHEMBL5141309 0.76 RXRA (0.59) LMNAKDM4ETSHRHSD17B10SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076734-A1 COMPOSITE MATERIAL COMBINING MOF NANOPARTICLES AND METAL NANOPARTICLES Centre national de la recherche scientifique (FR) 2022-10-26 EP disclosed