Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30232540 | 0.84 | ALDH1A1 (0.38) | LMNATHRBL3MBTL1GPR55KIF18A | |
| SCHEMBL29932225 | 0.67 | GAA (0.40) | LMNATHRBGPR55ALDH1A1GAA | |
| SCHEMBL29932142 | 0.66 | PDE4B (0.33) | LMNAGAAHTTSMN1; SMN2HTR1A | |
| SCHEMBL23536497 | 0.64 | PAX8 (0.36) | LMNATHRBALDH1A1KDM4EGAA | |
| SCHEMBL29931763 | 0.64 | PAX8 (0.36) | LMNATHRBALDH1A1KDM4EGAA | |
| SCHEMBL23057075 | 0.64 | MCOLN3 (0.53) | LMNAL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL29931821 | 0.63 | MAPT (0.36) | LMNAALDH1A1KDM4EHTTTSHR | |
| SCHEMBL29932013 | 0.62 | MCOLN3 (0.48) | LMNAL3MBTL1KIF18AALDH1A1KDM4E | |
| SCHEMBL23535974 | 0.61 | MCOLN3 (0.50) | LMNAL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL23057263 | 0.60 | MCOLN3 (0.48) | LMNAL3MBTL1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076423-A1 | TRPML MODULATORS | Casma Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |