SCHEMBL299501

SCHEMBL299501

FC(F)(F)c1cscn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL9548534 0.95 CYP19A1 (0.40)
SCHEMBL6247886 0.80 CYP19A1 (0.40)
SCHEMBL8684511 0.77 AR (0.52)
SCHEMBL12368440 0.66 KDM4E (0.45)
SCHEMBL15038282 0.64 CYP19A1 (0.43)
SCHEMBL679401 0.64 NR1H2 (0.38)
SCHEMBL2406065 0.64 ALDH1A1 (0.36)
SCHEMBL446727 0.63
SCHEMBL7964249 0.61 TSHR (0.50)
SCHEMBL679244 0.61 SLC6A3 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070879-A1 ISOXAZOLINE DERIVATIVES ELANCO TIERGESUNDHEIT AG (CH) 2026-03-12 US claimed
US-12497370-B2 Isoxazoline derivatives ELANCO TIERGESUNDHEIT AG (CH) 2025-12-16 US claimed
US-20240051949-A1 HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2024-02-15 US claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
CN-104193693-A NOVEL HERBICIDES SYNGENTA LTD 2014-12-10 CN claimed
US-20260102404-A1 THYROID STIMULATING HORMONE RECEPTOR (TSHR) ANTAGONISTS AND USES THEREOF Crinetics Pharmaceuticals, Inc. (US) 2026-04-16 US disclosed
US-20260092061-A1 COMPOUNDS FOR TARGETED PROTEIN DEGRADATION AMPHISTA THERAPEUTICS LTD (GB) 2026-04-02 US disclosed
US-20260070896-A1 HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS UNIV LEUVEN KATH (BE) 2026-03-12 US disclosed
US-12435076-B2 Fluorine-containing pyrimidine compound and method for producing same UNIMATEC CO., LTD. (JP) 2025-10-07 US disclosed
US-12404266-B2 Heterocycle derivatives for treating TRPM3 mediated disorders KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-09-02 US disclosed
US-12240855-B2 Pyrrolopyrazole derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-03-04 US disclosed
EP-4423090-A2 ANTAGONISTS OF GPR39 PROTEIN Vasocardea, Inc. (US) 2024-09-04 EP disclosed
WO-2009147433-A1 HETEROCYCLIC UREA DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS ASTRAZENECA AB (SE) 2009-12-10 WO disclosed
US-20090233962-A1 Amide derivative and insecticide containing the same MITSUI CHEMICALS, INC. (JP) 2009-09-17 US disclosed
US-20090099204-A1 Amide derivative, insecticide containing the same and method for application thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2009-04-16 US disclosed
WO-2008132153-A1 NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2008-11-06 WO disclosed
CN-1036589-C New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO (JP) 1997-12-03 CN disclosed
CN-1074444-A New thiazolyl benzofuran derivative, its preparation method and contain the pharmaceutical composition of this derivative FUJISAWA PHARMACEUTICAL CO (JP) 1993-07-21 CN disclosed
CN-1070910-A New thiazolyl benzofuran derivative, its preparation method and contain the pharmaceutical composition of this derivative FUJISAWA PHARMACEUTICAL CO (JP) 1993-04-14 CN disclosed